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The announcement by the West Virginia Democrat dooms the $2 trillion social spending and climate legislation, which needs support from every Senate Democrat in order to pass through the 50-50 chamber.

Democratic West Virginia Senator Joe Manchin went on Fox News this morning and delivered what sounded like a fatal blow to Joe Biden's Build Back Better agenda.

Gabriel Boric, 35, defeated a far-right lawmaker in a divisive election. Poised to become Chile's youngest modern president, he's vowed to expand social services and boost environmental protections.

The virus is the enemy, NIH Director Francis Collins said. "It's not the other people in the other political party." Omicron, which could soon become the dominant strain, is extremely infectious.

President Biden is expected to address the surge in omicron cases, but is his administration's response fast and sufficient enough to meet what could be the most challenging month yet in the pandemic?

Scientists have finally found a millipede that lives up to its name. Eumillipes persephone has 1,306 legs — that's more than any other animal — and is the only known millipede to exceed 1,000 legs.

The seven-night cruise ended in Miami on Saturday after making three stops in the Caribbean. More than 6,000 people were on the ship, which required testing and those 12 and over to be vaccinated.

NPR's Ailsa Chang speaks with Ryan Stanley, the mayor of Joplin, Mo., about recovery efforts and lessons learned from the 2011 tornado that killed 161 people.

NPR's Ari Shapiro speaks with California Attorney General Rob Bonta about a recent spate of "smash and grab" incidents at California retailers.

Stocks dropped as investors worried about how the omicron variant would impact the global economy after several countries imposed restrictions.